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Pharmacology: Pharmacokinetics: Lithium alters sodium transport in nerve and muscle cells. It increases intraneuronal metabolism of catecholamines.
Lithium ions are readily absorbed when given orally. A plasma lithium peak is reached 2-4 hours after ingestion of lithium carbonate. Lithium is not bound to plasma proteins. The concentration in cerebrospinal fluid is only about half of that in plasma. The main route of excretion is through the kidneys.
